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[15] Ponce, C.; Razon, A. D.; Chao, J.; Nakagawa, S. K.; Peterson, M. M.; Roque, A. Y.; Vanderpool, M. A.; Ferracane, M. J.; Olson, L. E. Impact of an over-the-counter “sleep lotion” on salivary melatonin levels and sleep quality: a randomized controlled trial. Neuroendocrinol. Lett. 2024, 45, 167-172 [link]
[14] Brunicardi, J. E. H.; Griffin, J. H.; Ferracane, M. J.; Kreutzer, A. G.; Small, J.; Mendoza, A.-T.; Ziller, J. W.; Nowick, J. S. Structure-activity relationship studies of the peptide antibiotic clovibactin. J. Org. Chem. 2024, 89, 12479 [link]
[13] Gisemba, S. A.; Ferracane, M. J.; Murray, T. F.; Aldrich, J. V. A bicyclic analog of the linear peptide arodyn is a potent and selective kappa opioid receptor antagonist. Molecules 2024, 29, 3109 [link]
[12] Chongsaritsinsuk, J.; Steigmeyer, A. D.; Mahoney, K. E.; Rosenfeld, M. A.; Lucas, T. M.; Ince, D.; Kearns, F. L.; Battison, A. S.; Hollenhorst, M. A.; Shon, D. J.; Tiemeyer, K. H.; Attah, V.; Kwon, C.; Bertozzi, C. R.; Ferracane, M. J.; Amaro, R. E.; Malaker, S. A. Glycoproteomic landscape and structural dynamics of TIM family immune checkpoints enabled by mucinase SmE. Nat. Commun. 2023, 14, 6169 [link]
[11] Pedram, K.; Shon, D. J.; Tender, G. S.; Mantuano, N. R.; Northey, J. J.; Metcalf, K. J.; Wisnovsky, S. P.; Riley, N. M.; Forcina, G. C.; Malaker, S. A.; Kuo, A.; George, B. M.; Miller, C. L.; Casey, K. M.; Vilches-Moure, J. G.; Ferracane, M. J.; Weaver, V. M.; Laübli, H.; Bertozzi, C. R. Design of a mucin-selective protease for targeted degradation of cancer-associated mucins. Nat. Biotechnol. 2023 [link]
[10] Shon, D. J.; Fernandez, D.; Riley, N. M.; Ferracane, M. J.; Bertozzi, C. R. Structure-guided mutagenesis of a mucin-selective metalloprotease from Akkermansia muciniphila alters substrate preferences. J. Biol. Chem. 2022, 298, 101917 [link]
[9] Shon, D. J.; Kuo, A.; Ferracane, M. J.; Malaker, S. A. Classification, structural biology, and applications of mucin-targeting proteases. Biochem. J. 2021, 478, 1585-1603 [link]
[8] Haurat, M. F.; Scott, N. E.; Di Venanzio, G.; Lopez, J.; Pluvinage, B.; Boraston, A. B.; Ferracane, M. J.; Feldman, M. F. The glycoprotease CpaA secreted by medically relevant Acinetobacter species targets multiple O-linked host glycoproteins. mBio 2020, 11, e02033-20 [link]
[7] Malaker, S. A.; Pedram, K.; Ferracane, M. J.; Bensing, B. A.; Krishnan, V.; Pett, C.; Yu, J.; Woods, E. C.; Kramer, J. R.; Westerlind, U.; Dorigo, O.; Bertozzi, C. R. The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins. Proc. Natl. Acad. Sci. U. S. A. 2019, 116, 7278-7287 [link]
[6] Malaker, S. A.; Ferracane, M. J.; Depontieu, F. R.; Zarling, A. L.; Shabanowitz, J.; Bai, D. L.; Topalian, S. L.; Engelhard, V. H.; Hunt, D. F. Identification and characterization of complex glycosylated peptides presented by the MHC class II processing pathway in melanoma. J. Proteome Res. 2017, 16, 228-237 [link]
MENTORED CAREER:
MENTORED CAREER:
[5] Gisemba, S. A.; Ferracane, M. J.; Murray, T. F; Aldrich, J. V. Conformational Constraint between Aromatic Residue Side Chains in the “Message” Sequence of the Peptide Arodyn Using Ring Closing Metathesis Results in a Potent and Selective Kappa Opioid Receptor Antagonist. J. Med. Chem. 2021, 64, 3153-3164 [link]
[4] Brice-Tutt, A.; Wilson, L. L.; Eans, S. O.; Stacy, H. M.; Simons, C. A.; Simpson, G. G.; Coleman, J. S.; Ferracane, M. J.; Aldrich, J. V.; McLaughlin, J. P. Multifunctional Opioid Receptor Agonism and Antagonism by a Novel Macrocyclic Tetrapeptide Prevents Reinstatement of Morphine-Seeking Behavior. Br. J. Pharmacol. 2020, 177, 4209-4222 [link]
[3] Ferracane. M. J.; Brice-Tutt, A. C.; Coleman, J. S.; Simpson, G. G.; Wilson, L. L.; Eans, S. O.; Stacy, H. M.; Murray, T. F.; McLaughlin, J. P.; Aldrich, J. V. Design, Synthesis, and Characterization of the Macrocyclic Tetrapeptide cyclo[Pro-Sar-Phe-d-Phe]: a Mixed Opioid Receptor Agonist-Antagonist Following Oral Administration. ACS Chem. Neurosci. 2020, 11, 1324-1336 [link]
[2] Ferracane, M. J.; Aldrich, J. V. Opioid ligand binding to opioid receptors: insight and implications for peptide design. Proceedings of the 24th American Peptide Symposium 2015, 24, 22-23 [link]
[1] Lefever, M. R.; Szabo, L. Z.; Anglin, B.; Ferracane, M.; Hogan, J.; Cooney, L.; Polt, R. Glycosylation of α-amino acids by sugar acetate donors with InBr3. Minimally competent Lewis acids. Carbohydr. Res. 2012, 351, 121-125 [link]
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